Biocompatibility, Resorption, and Osteoconductivity
OsseoConduct™ is a state of the art micro-porous beta tricalcium phosphate that provides what you are looking for in a granular bone graft material — the only material of this category cleared by the FDA for implant placement.
Unlike its predecessors, this 3rd generation βTCP contains micro-pores rather than macro-pores. Recent studies concluded that macro-pores allowed for bacteria to become entrapped, causing bacterial colonization resulting in graft failure. As a matrix for cell adhesion and proliferation in combination with cell mediated resorption, OsseoConduct™ produces normal bone in a short time period.
OsseoConduct™ granules undergo a rapid rate of resorption due to its unique physical properties. Other resorbable granular bone grafts require osteoclasts for resorption to take place. Osteoclasts exist only in mineralized bone. In order for other bone graft materials to be resorbed, they must be encased in mineralized bone first before absorption can occur. Therefore, the resorption process will take many months or years. OsseoConduct™ granules are able to be resorbed by monocytes (phagocytes) which are found in soft connective tissue.
OsseoConduct™ granules begin the resorbative process soon after grafting. The process continues providing space for ingrowth of mineralized bone. The result is a rapid and complete replacement of OsseoConduct™ granules with normal bone while maintaining shape and volume. Unlike allografts and xenografts, OsseoConduct™ produces bone with normal physiology and architecture.